Genomics & Genetics Weekly
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Asthma
Findings from INSERM broaden understanding of asthma
December 12th, 2008
According to a study from Paris, France, "A genomewide association study has shown an association between variants at chromosome 17q21 and an increased risk of asthma. To elucidate the relationship between this locus and disease, we examined a large, family-based data set that included extensive phenotypic and environmental data from the Epidemiological Study on the Genetics and Environment of Asthma." "We tested 36 single-nucleotide polymorphisms (SNPs) in the 17q21 region in 1511 subjects from 372 families for an association with asthma. We also tested for genetic heterogeneity according to the age at the onset of asthma and exposure to environmental tobacco smoke in...
Source: Genomics & Genetics Weekly (2008-12-12)
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