Genomics & Genetics Weekly
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Breast Cancer
Studies from University of North Carolina update current data on breast cancer
December 12th, 2008
According to a study from the United States, "Peroxisome proliferator-activated receptor-alpha (PPARA) has been shown to increase fatty acid oxidation and decrease cytokine levels and has been implicated in insulin production. Genetic variants of PPARA have been associated with cardiovascular disease, obesity and type II diabetes mellitus." "Although no research to date has investigated the possible link between PPARA and breast cancer, the function of this gene suggests that it could play a role in breast cancer development. Six PPARA polymorphisms were evaluated in association with incident breast cancer in a populationbased case -control study (n = 1073 cases and n =...
Source: Genomics & Genetics Weekly (2008-12-12)
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