Genomics & Genetics Weekly
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Breast Disease
Scientists at INSERM publish new data on breast disease
December 12th, 2008
According to recent research from Paris, France, "There is currently no known genetic disease linked to prolactin (Prl) or its receptor (PrIR) in humans. Given the essential role of this hormonal system in breast physiology, we reasoned that genetic anomalies of Prl/PrIR genes may be related to the occurrence of breast diseases with high proliferative potential." "Multiple fibro-adenomas (MFA) are benign breast tumors which appear most frequently in young women, including at puberty, when Prl has well-recognized proliferative actions on the breast. In a prospective study involving 74 MFA patients and 170 control subjects, we identified four patients harboring a...
Source: Genomics & Genetics Weekly (2008-12-12)
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