Genomics & Genetics Weekly
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Gene Therapy
Royal Children's Hospital publishes research in gene therapy
December 12th, 2008
"Human placentation displays many similarities with tumourigenesis, including rapid cell division, migration and invasion, overlapping gene expression profiles and escape from immune detection. Recent data have identified promoter methylation in the Ras association factor and adenomatous polyposis coli tumour suppressor genes as part of this process," scientists in Parkville, Australia report. "However, the extent of tumour-associated methylation in the placenta remains unclear. Using whole genome methylation data as a starting point, we have examined this phenomenon in placental tissue. We found no evidence for methylation of the majority of common tumour suppressor...
Source: Genomics & Genetics Weekly (2008-12-12)
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