Genomics & Genetics Weekly
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Gene Therapy
Studies from National Autonomous University add new findings in the area of gene therapy
December 12th, 2008
"The acquisition of new genetic traits by horizontal gene transfer and their incorporation into preexisting regulatory networks have been essential events in the evolution of bacterial pathogens. An example of successful assimilation of virulence traits is Salmonella enterica, which acquired, at distinct evolutionary times, Salmonella pathogenicity island 1 (SPI-1), required for efficient invasion of the intestinal epithelium and intestinal disease, and SPI-2, essential for Salmonella replication and survival within macrophages and the progression of a systemic infection," scientists in Cuernavaca, Mexico report. "A positive regulatory cascade mainly composed of HilD,...
Source: Genomics & Genetics Weekly (2008-12-12)
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