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Research from S. Kasraie et al has provided new information about life sciences

Published in Genomics and Genetics Weekly, December 26th, 2008

A report, 'Investigation of tRNA(Leu/Lys) and ATPase 6 genes mutations in Huntington's disease,' is newly published data in Cellular and Molecular Neurobiology. According to a study from Iran, "Huntington disease (HD) is a genetically dominant condition caused by expanded CAG repeats which code for glutamine in the HD gene product, huntingtin. Huntingtin is expressed in almost all tissues, so abnormalities outside the brain can also be expected."

"Involvement of nuclei and mitochondria in HD pathophysiology has been suggested. In fact mitochondrial dysfunction is reported in brains of patients suffering from HD. The tRNA gene mutations are one of hot spots that...

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