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Genomics & Genetics Weekly

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RNA Research



Data on RNA research reported by A. Zaborin and co-researchers



June 19th, 2009

According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "During host injury, Pseudomonas aeruginosa can be cued to express a lethal phenotype within the intestinal tract reservoir-a hostile, nutrient scarce environment depleted of inorganic phosphate. Here we determined if phosphate depletion activates a lethal phenotype in P. aeruginosa during intestinal colonization."

"To test this, we allowed Caenorhabditis elegans to feed on lawns of P. aeruginosa PAO1 grown on high and low phosphate media. Phosphate depletion caused PAO1 to kill 60% of nematodes whereas no worms died on high...


Source: Genomics & Genetics Weekly (2009-06-19)

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