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Adenoma
Research reports from University of South Carolina provide new insights into adenoma
June 19th, 2009
According to recent research published in the International Journal of Colorectal Disease, "Cyclooxygenase (COX) enzymes, COX1 and COX2, are key in converting arachidonic acid (AA) into prostaglandins that have been associated with colorectal carcinogenesis. The aim of our study was to investigate associations of polymorphisms in COX genes, alone and in interaction with exposures known to be related to inflammation and AA metabolism, with risk of colorectal adenomas." "In a community-, colonoscopy-based case-control study with 162 incident, sporadic colorectal adenoma cases and 211 controls, we investigated associations of two promoter polymorphisms (-842 A> G...
Source: Genomics & Genetics Weekly (2009-06-19)
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