Genomics & Genetics Weekly
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Alzheimer Disease
Data on Alzheimer disease detailed by researchers at Technical University of Munich
June 19th, 2009
In this recent study, researchers in Munich, Germany conducted a study "To examine the influence of the APOE genotype on levels of beta-amyloid (A beta) plaque load and atrophy in patients with Alzheimer disease (AD) in vivo. Thirty-two patients with moderate AD were divided into carriers and noncarriers of the epsilon 4 allele." "These groups were matched for age, disease duration, education, and cognitive impairment. In all subjects, [C-11]PIB-PET was performed for measurement of cerebral A beta plaque deposition and cranial MRI for the assessment of gray matter volume by voxel-based morphometry (VBM) and for correction of partial volume effects (PVE) in the PET data....
Source: Genomics & Genetics Weekly (2009-06-19)
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