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Genomics & Genetics Weekly

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Aneurysm



Research from Turku University broadens understanding of aneurysm



June 19th, 2009

"After aneurysmal subarachnoid hemorrhage (SAH), conflicting results concerning an association between the APOE genotype and impaired outcome have been reported. The authors tested prospectively whether APOE epsilon 2 or epsilon 4 allele-containing genotypes (epsilon 2+ and epsilon 4+) affect outcome after SAH," researchers in Turku, Finland report.

"Previous disease histories and clinical and radiological variables were recorded for 105 patients who were admitted within 48 hours after SAH. Fifteen patients (14%) had the epsilon 2+ genotype and 31 (17%) had epsilon 4+ genotypes. Factors predicting poor outcome according to the Glasgow Outcome Scale and cerebral...


Source: Genomics & Genetics Weekly (2009-06-19)

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