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Autoimmune Disease
New autoimmune disease study findings have been reported from University of Pisa
July 10th, 2009
According to a study from Pisa, Italy, "Azathioprine (AZA) is a purine antimetabolite, prodrug widely used as a disease modifying drug in several rheumatic conditions. The aim of the present,study was to evaluate the prevalence of TPMT genetic polymorphisms in a cohort of Italian Caucasian patients affected by rheumatic diseases and treated with AZA, and to establish correlations with the tolerability of AZA treatment." "Seventy-eight Caucasian patients, 16 males and 62 females, median age 41 years (min-max: 24-76) were enrolled. At the tune of evaluation, the median duration of treatment with AZA was 8 months (min-max: 2-150 months); the median close of AZA per kg of...
Source: Genomics & Genetics Weekly (2009-07-10)
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