Genomics & Genetics Weekly
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Life Sciences
Studies by S. De and co-authors describe new findings in life sciences
July 10th, 2009
According to a study from Cambridge, the United Kingdom, "Divergence of gene expression can result in phenotypic variation, which contributes to the evolution of new species. Although the influence of trans- and cis-regulatory mutations is well known, the genome-wide impact of changes in genomic neighborhood of genes on expression divergence between species remains largely unexplored." "Here, we compare the neighborhood of orthologous genes (within a window of 2 MB) in human and chimpanzee with the expression levels of their transcripts from several equivalent tissues and demonstrate that genes with altered neighborhood are more likely to undergo expression divergence...
Source: Genomics & Genetics Weekly (2009-07-10)
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