Cervical Intraepithelial Neoplasia Genetics
Study data from Nippon Medical School, Department of Pathology update knowledge of cervical intraepithelial neoplasia genetics
Published in Genomics and Genetics Weekly, March 26th, 2010
Researchers detail in 'Expression of fibroblast growth factor receptor 2 IIIc in human uterine cervical intraepithelial neoplasia and cervical cancer,' new data in cervical intraepithelial neoplasia. "Fibroblast growth factor receptors (FGFRs) 1-3 have IIIb and IIIc isoforms, and we reported that FGFR2 IIIb is highly expressed in cervical keratinizing squamous cell carcinoma (SCC). In this study, we determined the expression and roles of FGFR2 IIIc in cervical intraepithelial neoplasia (CIN) and cervical cancer," investigators in Tokyo, Japan report.
"In CINs 1 and 2, FGFR2 IIIc was found to be localized at the basal to lower two-thirds of the squamous epithelium,...
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