The Mount Sinai Hospital / Mount Sinai School of Medicine
Mount Sinai researchers discover genetic framework to explain and predict adverse drug reactions
Published in Genomics and Genetics Weekly, May 7th, 2010
In a new study, researchers at Mount Sinai School of Medicine have taken a major step toward the ability to predict adverse drug reactions, using genetic, cellular, and clinical information to learn why some medicines cause heart arrhythmias in patients. Published in the April 20 issue of the journal Science Signaling, the new framework described in the study could potentially be applied to the study of medications that treat other diseases and disorders such as epilepsy and autism.
Researchers have learned over the last decade that human genetic make-up contains slight variations that can alter individual responses to medications. Led by Ravi Iyengar, PhD, Dorothy H...
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