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Breast Cancer

Reports outline breast cancer study findings from University Hospital, Institute for Cancer Research

Published in Genomics and Genetics Weekly, June 11th, 2010

Data detailed in 'Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer' have been presented. "Ductal carcinoma in situ (DCIS) is a non-invasive lesion of the breast that is frequently detected by mammography and subsequently removed by surgery. However, it is estimated that about half of the detected lesions would never have progressed into invasive cancer," scientists writing in the journal Breast Cancer Research report.

"Identifying DCIS and invasive cancer specific epigenetic lesions and understanding how these epigenetic changes are involved in triggering tumor progression is...

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