Center for Cellular and Molecular Biology, Hyderab
NKG2D likely dendritic cell target-recognition molecule
Published in Health Business Week, June 11th, 2004
"DC are the most efficient antigen-presenting cells that regulate the immune response," scientists in India noted.
In their study, R. Alli and colleagues at the Center for Cellular and Molecular Biology in Hyderabad demonstrated the "expression of NK cell receptor protein-2 (NKR-P2) on rat and mouse DC," and the fact that "NKR-P2 gets reorganized upon antigen contact."
"DC activated with anti-NKR-P2 mAb exhibit enhanced apoptotic killing of tumor targets, whereas blocking the interaction between NKR-P2 and its ligand with rNKR-P2 abrogated...
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Source: Health Business Week (2004-06-11)
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