Inst. of Nephrology and Urology, Montevideo

Effect of anti-CD3 mAb dose on T-cell count determined

Published in Health Business Week, November 12th, 2004

The effect of anti-CD3 mAb dose on T-cell count has been determined.

"The monoclonal anti-CD3 antibody is used as part of prophylaxis and also in treatment of rejection," scientists in Uruguay explained.

In a recent study, F. Gonzalez-Martinez and colleagues at the Institute of Nephrology and Urology in Montevideo "analyzed changes in different lymphocyte subpopulations after anti-CD3 treatment."

"T lymphocytes were decreased under anti-CD3 antibody administration, with a simultaneous increase in B lymphocytes but no changes in natural killer (NK) cells," test results showed. "No differences were found between patients...

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Source: Health Business Week (2004-11-12)

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