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Hana Biosciences, Inc.

Company initiates phase I/II clinical trial of talotrexin in patients with ALL

Published in Health Business Week, June 10th, 2005

Hana Biosciences, Inc., (HNAB), a South San Francisco, California-based biopharmaceutical company focused on advancing cancer care, announced the initiation of a phase I/II clinical study of talotrexin (PT-523) as a single agent in adult patients with relapsed or refractory acute lymphoblastic leukemia (ALL).

The phase I portion of this multicenter study will determine the dose, safety, tolerability, and pharmacokinetics of talotrexin in refractory leukemia patients, including both myeloid and lymphoid leukemias. The phase II component will focus on relapsed or refractory ALL patients to determine the efficacy of talotrexin, as measured by complete response rate.

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