Max Delbrueck Centre for Molecular Medicine

Tumor cells can weaken immune response

Published in Health Business Week, September 30th, 2005

Tumor cells can grow without control by weakening specific cells of the immune system, the T-cells, which normally detect and destroy tumor cells.

The findings of Dr. Gerald Willimsky and Prof. Thomas Blankenstein (Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch and Charité) were generated in transgenic mice over a period of 7 years and have now been published in the scientific journalNature. Until now, the notion was that tumor cells escape recognition and subsequent destruction by T-cells by hiding.

Furthermore, Dr. Willimsky and Prof. Blankenstein could show that the immune system recognizes tumors derived from single cells and...

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Source: Health Business Week (2005-09-30)

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