Published in Health Business Week, March 3rd, 2006
According to a recent report from investigators in the United States, "During ischemia intracellular concentrations of Pi and H+ increase. Also, changes in myosin heavy chain (MHC) isoform toward beta-MHC have been reported after ischemia and infarction associated with coronary artery disease."
"The purpose of this study was to investigate the effects of myoplasmic changes of Pi and H+ on the loaded shortening velocity and power output of cardiac myocytes expressing either alpha- or beta-MHC,"...
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