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Affymax, Inc.

Agreement signed to develop and commercialize Hematide in Japan

Published in Health Business Week, March 10th, 2006

Affymax, Inc., and Takeda Pharmaceutical Company Limited announced that the companies have entered into an exclusive agreement to develop and commercialize Affymax's lead product candidate, Hematide, in Japan for the treatment of anemia.

Hematide, a synthetic, peptide-based, next-generation erythropoiesis-stimulating agent (ESA), is designed to stimulate the production of red blood cells. It is currently being evaluated in four phase II clinical trials in the United States and Europe to treat anemia in chronic kidney disease (CKD) and cancer patients.

Pursuant to the agreement, Takeda will pay to Affymax US$17 million as an up-front payment and will...

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