Rudjer Boskovic Institute, Zagreb
Effect of indomethacin on E-cadherin and beta-catenin expression in colon cancer studied
Published in Health Business Week, March 10th, 2006
According to recent research from Croatia, "Nonsteroidal anti-inflammatory drugs (NSAIDs) lower the incidence of and mortality from colon cancer. Although there is much evidence from epidemiological and laboratory studies that NSAIDs have antitumor activity and reduce the incidence of colon cancer, the mechanism of action remains unknown."
"In this paper, we present the effect of indomethacin on growth inhibition, induction of apoptosis, and alterations in the expression of several genes involved in Wnt signaling in HT-29 colon cancer cells....
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Source: Health Business Week (2006-03-10)
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