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Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals initiates phase 2 development program for Aurora kinase inhibitor

Published in Health Business Week, May 5th, 2006

Vertex Pharmaceuticals Incorporated (VRTX) announced the initiation of a phase 2 clinical development program for VX-680, an investigational drug candidate targeting Aurora kinase.

In connection with the initiation of phase 2 development, Vertex earned a $10 million milestone payment in March 2006 from Merck & Co., Inc. Vertex and Merck have a global collaboration to develop and commercialize VX-680.

The initiation of phase 2 development for VX-680 is based on the enrollment of patients with advanced colorectal cancer in a phase 2 extension of a previous phase 1 clinical study. In addition, Merck expects to initiate a phase 2 clinical study for...

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