Stanford University, U.S.
Vascular endothelial growth factor modulates erythropoiesis
Published in Health Business Week, September 8th, 2006
"VEGF exerts crucial functions during pathological angiogenesis and normal physiology. We observed increased hematocrit (60-75%) after high-grade inhibition of VEGF by diverse methods, including adenoviral expression of soluble VEGF receptor (VEGFR) ectodomains, recombinant VEGF Trap protein and the VEGFR2-selective antibody DC101," scientists in the United States report.
"Increased production of red blood cells (erythrocytosis) occurred in both mouse and primate models, and was associated with near-complete neutralization of VEGF corneal micropocket...
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Source: Health Business Week (2006-09-08)
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