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BioMarin Pharmaceutical

BioMarin, Serono report data on Phenoptin

Published in Health Business Week, October 13th, 2006

BioMarin Pharmaceutical, Inc., (BMRN) and Serono (SEO, SRA) announced data from clinical studies of Phenoptin (sapropterin dihydrochloride), an investigational oral small-molecule therapeutic for the treatment of phenylketonuria (PKU), was presented at the 56th Annual Meeting of the American Society of Human Genetics (ASHG).

Results from a phase III, double-blind, placebo-controlled clinical study of Phenoptin (commonly referred to as 6R-BH4, or BH4) in patients with elevated blood phenylalanine (Phe) levels demonstrated a statistically significant reduction at 6 weeks in blood Phe levels (p<0.0001) in patients receiving 10 mg/kg/day of Phenoptin, compared with those...

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