Kyoto Pharmaceutical University, Japan

New findings reported from Kyoto Pharmaceutical University, Department of Neurobiology describe advances in parkinson disease

Published in Health Business Week, November 3rd, 2006

Research findings, "PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model," are discussed in a new report. "DJ-1 has recently been shown to be responsible for onset of familial Parkinson's disease (PD), PARK7. DJ-1 has been shown to play roles in transcriptional regulation and anti-oxidative stress, and loss of its function is thought to trigger onset of PD," scientists in Kyoto, Japan report.

"In this study, a recombinant DJ-1 protein was administrated into the brain of PD model rats that had been injected to 6-hydroxydopamine (6-OHDA) in the left substantia nigra. PD phenotypes, including dopaminergic neuron death in...

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Source: Health Business Week (2006-11-03)

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