Pain Management

NicOx ABPM trial shows favorable blood pressure profile for naproxcinod

Published in Health Business Week, January 12th, 2007

NicOx S.A. (NICOX) announced top-line results from a pharmacodynamic clinical study utilizing ambulatory blood pressure monitoring (ABPM), which demonstrated a differentiated and favorable 24-hour blood pressure profile for naproxcinod, compared to naproxen, in hypertensive subjects after two weeks.

The trial results showed a 2 mmHg difference in both the average systolic and diastolic blood pressure in favor of naproxcinod, in terms of the mean change from baseline as measured by ABPM. This difference did not reach statistical significance for systolic blood pressure, the primary endpoint of the trial (p=0.101).

However statistical significance was...

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Source: Health Business Week (2007-01-12)

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