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HIV/AIDS Therapy

GlaxoSmithKline discontinues clinical development of HIV protease inhibitor brecanavir

Published in Health Business Week, January 19th, 2007

GlaxoSmithKline, plc, (GSK) announced that, due to insurmountable issues regarding formulation, development of brecanavir, an investigational protease inhibitor for the treatment of HIV, has been discontinued.

Brecanavir was in phase II clinical development.

Clinical trial investigators have been notified and directed to transition their patients to marketed antiretrovirals, or appropriate treatments available through expanded access programs.

"GSK is dedicated to excellence in the care of individuals with HIV infection, and we will continue our efforts to find effective treatments with improved resistance profiles for these...

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