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Sickle Cell Disease

Anthera gets approval to start phase II IMPACTS trial in patients with sickle cell disease

Published in Health Business Week, February 9th, 2007

Anthera Pharmaceuticals, Inc. announced that the U.S. Food and Drug Administration has approved its Investigational New Drug (IND) application for use of its lead compound A-001 in hospitalized patients with sickle cell disease.

The IMPACTS (Investigation of the Modulation of Phospholipase in Acute ChesT Syndrome) trial is a multicenter phase 2 clinical study aimed at preventing a severe respiratory complication of sickle cell disease, acute chest syndrome. Acute chest syndrome, a form of acute lung injury, is the leading cause of death in sickle cell disease patients. It commonly follows admission to the hospital for other reasons, especially an episode of bone pain (a...

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