Alzheimer Disease

New gene uncovered for Alzheimer disease

Published in Health Business Week, February 16th, 2007

Robert Friedland, MD, professor in the Department of Neurology, and a team of investigators at Case School of Medicine, in collaboration with an international effort by researchers led by Boston University School of Medicine, the University of Toronto and Columbia University Medical Center, have uncovered a major new gene - SORL1 - for late-onset Alzheimer disease.

Replicated in four distinct ethnic groups, SORL1 is only the second gene discovered for late-onset Alzheimer. APOE, the first gene, was identified in 1993.

In an article published in Nature Genetics, researchers describe how variants in the SORL1 gene were found to be more common in...

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Source: Health Business Week (2007-02-16)

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