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Acne Vulgaris

CollaGenex Pharmaceuticals Initiates 40 mg Cohort in the Phase II Dose-Finding Study of Incyclinide for the Treatment of Acne

Published in Health Business Week, April 13th, 2007

CollaGenex Pharmaceuticals, Inc. (NASDAQ:CGPI) announced that it has initiated enrollment in a 40 mg cohort in its Phase II double-blinded, placebo-controlled, dose-finding clinical trial to determine the appropriate dose for Phase III testing of incyclinide in the treatment of acne. The 40 mg cohort will enroll 100 patients with moderate-to-severe acne at 13 investigational centers across the United States. The placebo-controlled study will evaluate a daily 40 mg dose of incyclinide over a 12 week period.

Klaus Theobald, M.D., Ph.D., chief medical officer of CollaGenex, said, "We are extremely encouraged that the analysis of the 5, 10, and 20 mg cohorts demonstrated a...

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