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Adverse Drug Reactions

UCB Announces Positive Top-Line Phase III Results for Keppra as Adjunctive Therapy for Partial Onset Seizures in Paediatric Patients from One Month to Less than Four Years of Age

Published in Health Business Week, May 11th, 2007

UCB today announced positive top-line results from a phase III, double-blind, randomized, multi-centre, placebo-controlled study evaluating the efficacy and tolerability of Keppra(R) (levetiracetam) (20-50 mg/kg/day) as adjunctive therapy in the treatment of partial onset seizures in children (n=116) from one month to less than four years of age. Compared with placebo, Keppra(R) was shown to significantly reduce the frequency of partial onset seizures in these paediatric patients with consistent results across all stratified age groups.

Commenting on the results, Jes's Eric Pi'a-Garza M.D., Professor of Paediatric Neurology & Director Pediatric Epilepsy Clinical Trials,...

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