Immunology
Research from RIKEN provide new insights into immunology
Published in Health Business Week, October 19th, 2007
Fresh data on immunology are presented in the report 'T cell lineage determination precedes the initiation of TCRbeta gene rearrangement.' According to recent research from Yokohama, Japan, "Loss of dendritic cell potential is one of the major events in intrathymic T cell development, during which the progenitors become determined to the T cell lineage. However, it remains unclear whether this event occurs in synchrony with another important event, TCRbeta chain gene rearrangement, which has been considered the definitive sign of irreversible T cell lineage commitment."
"To address this issue, we used transgenic mice in which GFP expression is controlled by the lck...
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Source: Health Business Week (2007-10-19)
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