Life Sciences
Research on life sciences detailed by scientists at Dow Chemical Company
Published in Health Business Week, December 21st, 2007
Data detailed in 'The effect of route, vehicle, and divided doses on the pharmacokinetics of chlorpyrifos and its metabolite trichloropyridinol in neonatal Sprague-Dawley rats' have been presented. "There is a paucity of data on neonatal systemic exposure using different dosing paradigms. Male CD (Sprague-Dawley derived) rats at postnatal day (PND) 5 were dosed with chlorpyrifos (CPF, 1 mg/kg) using different routes of exposure, vehicles, and single versus divided doses," scientists writing in the journal Toxicological Sciences report.
"Blood concentrations of CPF and its primary metabolite, trichloropyridinol, were measured at multiple times through 24 h. Groups...
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Source: Health Business Week (2007-12-21)
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