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Alzheimer Disease
Lilly Launches Its First Phase III Trial for Treatment of Alzheimer's Disease
April 18th, 2008
Eli Lilly and Company (NYSE:LLY) has announced the start of a Phase III clinical trial studying LY450139, an investigational gamma secretase inhibitor for the treatment of mild to moderate Alzheimer's disease. LY450139 is being tested to see if it can slow the progression associated with Alzheimer's disease by inhibiting gamma-secretase, an enzyme that can create a sticky protein called amyloid beta. Current Alzheimer's disease theory is that subtypes of amyloid beta clump together into plaques that eventually kill off brain cells. By blocking gamma secretase, there is less amyloid beta formed, potentially slowing brain-cell death. Slowing the rate of disease...
Source: Health Business Week (2008-04-18)
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