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Hematopoiesis
New hematopoiesis study results from RIKEN described
May 16th, 2008
According to a study from Yokohama, Japan, "During haematopoiesis, pluripotent haematopoietic stem cells are sequentially restricted to give rise to a variety of lineage-committed progenitors. The classical model of haematopoiesis postulates that, in the first step of differentiation, the stem cell generates common myelo-erythroid progenitors and common lymphoid progenitors (CLPs)." "However, our previous studies in fetal mice showed that myeloid potential persists even as the lineage branches segregate towards T and B cells(1-6). We therefore proposed the 'myeloid-based' model of haematopoiesis(7,8), in which the stem cell initially generates common myelo-erythroid...
Source: Health Business Week (2008-05-16)
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