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Health Business Week

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Life Sciences



Findings from Wyeth in life sciences reported



May 16th, 2008

Researchers detail in 'Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory,' new data in life sciences. According to recent research from the United States, "Estrogens have long been implicated in influencing cognitive processes, yet the molecular mechanisms underlying these effects and the roles of the estrogen receptors alpha (ERalpha) and beta (ERbeta) remain unclear. Using pharmacological, biochemical and behavioral techniques, we demonstrate that the effects of estrogen on hippocampal synaptic plasticity and memory are mediated through ERbeta."

"Selective ERbeta agonists increased key synaptic proteins in vivo,...


Source: Health Business Week (2008-05-16)

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