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Life Sciences
Studies from Sequenom Inc. provide new data on life sciences
May 16th, 2008
"High single-channel conductance K+ channels, which respond jointly to membrane depolarization and micromolar concentrations of intracellular Ca2+ ions, arise from extensive cell-specific alternative splicing of pore-forming a-subunit mRNAs. Here, we report the discovery of an endogenous BKCa channel alpha-subunit intron-containing mRNA in the cytoplasm of hippocampal neurons," scientists in the United States report. "This partially processed mRNA, which comprises approximate to 10% of the total BKCa channel a-subunit mRNAs, is distributed in 6 gradient throughout the somatodendritic space. We selectively reduced endogenous cytoplasmic levels of this intron-containing...
Source: Health Business Week (2008-05-16)
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