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Health Business Week

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Tissue Engineering



Research from Neurocrine Biosciences, Inc. provides new data on tissue engineering



May 16th, 2008

"This paper describes the application of de novo design utilizing exclusively ligand information," scientists in the United States report.

"In the current approach, ligand design criteria, including pharmacophores, similarity and desired properties are applied as part of a fitness function driving the design process, instead of using them as filters after the process. This allows relevant parts of chemical space to be explored more efficiently," wrote M. Feher and colleagues, Neurocrine Biosciences, Inc.

The researchers concluded: "Two case studies of successful ligand design are also presented, one aimed at scaffold hopping, the other for exploring...


Source: Health Business Week (2008-05-16)

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