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Published in Health Business Week, August 14th, 2009

Researchers detail in 'Ca2+ increases the specific coenzyme Q10 content in Agrobacterium tumefaciens,' new data in life sciences. According to a study from Seoul, Korea, "Of various metal ions (Ca2+, Cr3+, Cu2+, Fe2+, Mg2+, Mn2+, Ni2+ and Zn2+) added to the culture medium of Agrobacterium tumefaciens at 1 mM, only Ca2+ increased Coenzyme Q10 (CoQ(10)) content in cells without the inhibition of cell growth. In a pH-stat fed-batch culture, supplementation with 40 mM of CaCO3 increased the specific CoQ(10) content and oxidative stress by 22.4 and 48%, respectively."

"Also, the effect of Ca2+ on the increase of CoQ(10) content was successfully verified in a pilot-scale (300...

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