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Allergies

'Good Clostridia' in the Gut Protect from Allergy and Autoimmunity

Published in Health Business Week, January 7th, 2011

2011 JAN 7 -- Scientists at the University of Tokyo have discovered that specific gut-dwelling bacteria control key immune cells that combat allergies and autoimmune diseases. The paper describing these findings was published in today's issue of the journal Science, and technology originating from the work is being advanced by start-up Vedanta Biosciences.

Dr. Kenya Honda and colleagues initially showed that mice raised in sterile conditions had deficient levels of regulatory T cells in their colon compared to mice colonized with microbes. "Regulatory T cells are the peace-keepers of the immune system," says Dr. Alexander Rudensky, tri-institutional...

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