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Health Insurance Week

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Pharmexa



New results published on Pharmexa's PADRE epitope in Alzheimer vaccine



October 1st, 2006

A group of scientists from the Institute of Molecular Medicine at Huntington Beach (California) and the Institute of Brain Aging and Dementia at the University of California has published new preclinical data on an experimental Alzheimer's vaccine incorporating Pharmexa's proprietary PADRE epitope.

The results were published in Vaccine (vol. 24, 2275-2282).

The prototype vaccine, a combination of a fragment of the Abeta peptide and Pharmexa's PADRE epitope, gave rise to high anti-Abeta antibody titers in vaccinated mice. No unwanted cellular immune responses were detected, and there were no signs of side effects in the brains of the...


Source: Health Insurance Week (2006-10-01)

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