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Autonomous University of Barcelona
Knockout mice show interleukin-6 helps the brain cope with injury
March 22nd, 2005
Knockout mice show interleukin-6 helps the brain cope with injury. "Traumatic injury to the brain is one of the leading causes of injury-related death or disability. Brain response to injury is orchestrated by cytokines such as interleukin (IL)-6, but the full repertoire of responses involved is not well known. We here report the results obtained with microarrays in wild-type and IL-6 knockout mice subjected to a cryolesion of the somatosensorial cortex and killed at 0, 1, 4, 8 and 16 days post-lesion," scientists in Spain report. "Overall gene expression was analyzed by using Affymetrix genechips/oligonucleotide arrays with approximately 12,400...
Source: Health Risk Factor Week (2005-03-22)
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