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Auburn University
Efficient synthesis of 5'-homoaristeromycin reported
March 22nd, 2005
Scientists have developed an efficient synthesis of 5'-homoaristeromycin. "An efficient synthesis of 5'-homoaristeromycin has been developed. This permitted an extensive antiviral analysis, which found potent activity toward vaccinia, cowpox, and monkeypox viruses," investigators in the United States report. "For comparative purposes, 5'-homoadenosine was made available by a newly designed route and found to be inactive," wrote Minmin Yang and Stewart W. Schneller at Auburn University. Yang and Schneller published their study in Bioorganic and Medicinal Chemistry Letters (5'-Homoaristeromycin. Synthesis and antiviral...
Source: Health Risk Factor Week (2005-03-22)
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