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AUSL Rimini

CD4 count at end of HAART interruption influences duration of first interruption

Published in Health Risk Factor Week, April 11th, 2006

Scientists are investigating the use of a strategy of HIV treatment interruption based on CD4+ cell counts.

Researchers in Italy conducted a study to "evaluate the safety of treatment interruption (TI) guided by CD4+ count in HIV-infected patients followed-up prospectively."

A. Boschi and colleagues at AUSL Rimini explained, "Patients on HAART with a CD4+ cell count >500 cells/mm3 discontinued therapy with instructions to start therapy again before their CD4+ count dropped below 200 cells/mm3. We report data on 112 HIV-infected patients."

"The median follow-up after starting the first TI was 34.7 months...

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