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Aspergillosis Immunology

New aspergillosis immunology research has been reported by scientists at Institute of Genomics and Integrative Biology

Published in Health Risk Factor Week, May 22nd, 2007

A new study, "Protective role of mannan-binding lectin in a murine model of invasive pulmonary aspergillosis," is now available. "Innate immune molecules such as lung collectins and serum pentraxins have evolved as important host defence proteins against Aspergillus fumigatus, a medically important opportunistic fungal pathogen. Mannan-binding lectin (MBL), an opsonin and lectin complement pathway activator, constitutes another vital player of innate immunity against several pathogenic organisms in the serum," researchers in Delhi, India report.

"Studies have reported significant binding of MBL to A. fumigatus; however, the protective role of MBL against...

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