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Colon Cancer Risk Factors

Findings from Karolinska Institut provide new insights into colon cancer risk factors

Published in Health Risk Factor Week, July 24th, 2007

Data detailed in "Lack of an association between the TGFBR1*6A variant and colorectal cancer risk" have been presented. According to recent research published in the journal Clinical Cancer Research, "Recently a common variant of the TGFBR1 gene, TGFBR1*6A, has been proposed to act as a low-penetrance tumor susceptibility allele for colorectal cancer, but data from published studies with individually low statistical power are conflicting. To further evaluate the relationship between TGFBR1*6A and colorectal cancer risk, we have conducted a large case-control study and a meta-analysis of previously published studies."

"A total of 1,042 colorectal cancer cases and...

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