Breast Cancer

Research conducted at Seoul National University has provided new information about breast cancer

Published in Health Risk Factor Week, January 8th, 2008

According to recent research from Seoul, South Korea, "Endothelial nitric oxide synthase (NOS3) produces nitric oxide which is a mediator of cytotoxic effects potentially associated with breast cancer. We evaluated the role of genetic polymorphisms of NOS3 in breast cancer etiology, in a case-control study conducted in Korea."

"We recruited 1,385 eligible patients with histologicaly confirmed incident breast cancer cases and 968 hospital-based controls. Two potentially functional NOS3 polymorphisms in the promoter region (-786T > C) and exon 7 (894G > T, Glu298Asp) were genotyped and individual haplotypes were estimated. Odds ratios (ORs) and 95% confidential...

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Source: Health Risk Factor Week (2008-01-08)

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