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Bird Flu

New bird flu research reported from A.J. Karpala and co-authors

Published in Health Risk Factor Week, April 8th, 2008

According to recent research published in the journal Developmental and Comparative Immunology, "Toll-like receptors (TLRs) play key roles in the response to pathogens and in mammals the host response to virus critically relies on TLR3 to detect viral-derived dsRNA. However, in chickens there is a paucity of information about this pathway, and in view of the recent concerns with regard to highly pathogenic avian influenza, there is a clear need for understanding these antiviral pathways."

"Furthermore, TLR3 engagement is important to the outcome of viral infection because of its role in the induction of interferons (IFNs) and the diverse antiviral effects that...

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