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Influenza

Report summarizes influenza study findings from L.A. Perrone and co-researchers

Published in Health Risk Factor Week, December 16th, 2008

"Fatal human respiratory disease associated with the 1918 pandemic influenza virus and potentially pandemic H5N1 viruses is characterized by severe lung pathology, including pulmonary edema and extensive inflammatory infiltrate. Here, we quantified the cellular immune response to infection in the mouse lung by flow cytometry and demonstrate that mice infected with highly pathogenic (HP) H1N1 and H5N1 influenza viruses exhibit significantly high numbers of macrophages and neutrophils in the lungs compared to mice infected with low pathogenic (LP) viruses," scientists in the United States report.

"Mice infected with the 1918 pandemic virus and a recent H5N1 human isolate...

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